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Below are interesting stocks on the NYSE and NASDAQ that are the highest gainers.

Columbia Bancorp (NASDAQ: CBBO) shares have appreciated by 40.51% since its last closing. CBBO shares have slipped by 69.55% over the past 52 weeks.

Clark Holdings Inc (NYSE: GLA) shares have appreciated by 39.98% since its last closing. GLA shares have plummeted by 59.09% over the past 52 weeks.

Hooper Holmes Inc (NYSE: HH) shares have appreciated by 30.26% since its last closing. HH shares are trading at a price significantly lower than their 52-week high of $1.16.

Axcelis Technologies Inc (NASDAQ: ACLS) shares have appreciated by 29.88% since its last closing. ACLS shares are trading at a price significantly lower than their 52-week high of $1.78.

Provident Financial Holdings Inc (NASDAQ: PROV) shares have appreciated by 17.65% since its last closing. PROV shares have declined by 35.07% over the past 52 weeks.

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Following are the few stocks which are moving up without any news on very unusual volume - this normally signals that either there is some news in pipeline or someone is speculating those stocks: –
Mountain Province Diamonds, Inc. (AMEX: MDM) spurted 34% with a volume of 684K shares against an average volume of 19K shares – over 35X. Currently the stock is stock is trading at $2.26, well above it 50-day and 200-day EMA.

Columbia Bancorp (NASDAQ: CBBO) is among the top percentage gainers in morning trade and surged 155 to $3.03 on huge volume of 381K shares on no news. The stock has a 52-week range of $049-$8.08.

Mountain Province Diamonds, Inc. (AMEX: MDM) rallied 46% on 468K shares and now trades at $2.45 on no news. Till now during the current calendar year the stock has surged over 200%.

Boston Private Financial Holdings Inc (NASDAQ: BPFH) is also moving higher by 26% to $6.77 after it announced the sale of RINET Company, LLC, to the RINET management team. Financial term were not disclosed.

Speedus Corp. (SPDE) I took my loss quickly, when it was clear afterhours and premarket that the short sellers would try to knock it down quickly to scare away any and all momentum buyers…yes, it happens, took a $700+ loss and didn’t even consider buying or shorting it the rest of the day since I didn’t know what the shorts were doing and what was actually real…when there’s confusion, I just don’t trade it.[More...]

Cbbo is near the 52 wk low.  This is a very strong stock that has shown continual growth over the past several years.  The bank was hit by defaulted loans, but has a good leadership and is not in danger of going under.  The bank has set a target of being back in the $15-20 range by 2010.